Just port SCUMM VM (http://www.scummvm.org/) and you can have this and dozens of other games.
Of course, the graphics wouldn’t take advantage of the 3D display, but maybe with some changes to the engine and ScummC (http://alban.dotsec.net/7.html) you could make a 3D Mansion (or, even better, Full Throttle or the Kyrandia series ;-))
As for the saving, you could use codes like Gobliiins (another SCUMM game).